P2161 Humber 6 is defined as Camshaft Position Sensor A Circuit Low. This means the CMP (camshaft position) sensor circuit on engine bank 1 sends an irregular reading. The spark should have a light tan color. If the sensor probe comes with white and chalky parts, this means it has been lagging between switching phases, and should be replaced.
Possible Causes :
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With the valve disconnected, the red voltmeter lead should be attached to the IMRC valve power wire and the black voltmeter lead connected to ground. If the scan tool has that capability, and the scan tool can operate the IMRC valves, then the problem is either resolved and a simple code clearing is all that's left or a new PCM would be called for. Replace the oxygen sensor that is downstream from the catalytic converter on the side of the engine that does not contain cylinder #1. Also, if a oxygen sensor code stating "heater circuit malfunction" the sensor has most probably failed.
Diagnostic trouble code P2161 Humber 6 is not difficult to diagnose and repair. Thus, it always pays to have a qualified technician to look after your vehicle should this error code arise.
Diagnosing this code requires the engine to be in good running shape, without unmetered air entering the engine. If other codes that relates to misfiring condition, lean running or air entering the engine is present, then you must first fix those error codes before P2161 Humber 6.
Fortunately, P2161 Humber 6 is a fairly common OBD code, meaning that it applies to all makes and models of vehicles made after 1996.