C0543 Skoda S shows up when there's an electrical problem that causes the fuel volume regulator to malfunction and open. It's quite an unusual problem and likely intermittent. As you drive and when specific conditions are slowly met, the vapors will gradually purge from the charcoal canister and will get burned within your engine.
Possible Causes :
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If the scan tool has that capability, and the scan tool can operate the IMRC valves, then the problem is either resolved and a simple code clearing is all that's left or a new PCM would be called for. With the valve disconnected, the red voltmeter lead should be attached to the IMRC valve power wire and the black voltmeter lead connected to ground. Oxygen sensors signal the engine management computer the amount of oxygen present in the exhaust, which is used in determining and controlling the fuel ratio.
Diagnostic trouble code C0543 Skoda S is not difficult to diagnose and repair. Thus, it always pays to have a qualified technician to look after your vehicle should this error code arise.
Diagnosing this code requires the engine to be in good running shape, without unmetered air entering the engine. If other codes that relates to misfiring condition, lean running or air entering the engine is present, then you must first fix those error codes before C0543 Skoda S.
Fortunately, C0543 Skoda S is a fairly common OBD code, meaning that it applies to all makes and models of vehicles made after 1996.