B2146 Mercedes R 350 is defined as Knock Sensor Circuit Range Performance (Bank 1 or Single Sensor). This refers to camshaft timing, which in this case is over-retarded. There are two wires dedicated for each coil; one is battery feed which usually comes from the distribution center, and the other one for the coil driver circuit from the PCM. The PCM grounds or ungrounds the circuit to activate or deactivate the coil.
Possible Causes :
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Find out what kind of system you have and verify that voltage to the fuel level sensor is present at the fuel pump wiring harness. If all testing has passed so far yet you still have the same code, check your scan tool and see if it can open and close the IMRC valve.
Diagnostic trouble code B2146 Mercedes R 350 is not difficult to diagnose and repair. Thus, it always pays to have a qualified technician to look after your vehicle should this error code arise.
Diagnosing this code requires the engine to be in good running shape, without unmetered air entering the engine. If other codes that relates to misfiring condition, lean running or air entering the engine is present, then you must first fix those error codes before B2146 Mercedes R 350.
Fortunately, B2146 Mercedes R 350 is a fairly common OBD code, meaning that it applies to all makes and models of vehicles made after 1996.