P2251 Seat 127 shows up when there's an electrical problem that causes the fuel volume regulator to malfunction and open. It's quite an unusual problem and likely intermittent. Other symptoms that may indicate this problem are when the Check Engine Light illuminates and when there is a visible lack of engine power.
Possible Causes :
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If the engine displays a miss and there wasn't a code, determine which cylinder is misfiring. If the exhaust manifold is visible, spay or pour a small amount of water on each cylinder exhaust port. Water will evaporate immediately on good cylinders and slowly on the missing cylinder. If this can't be accomplished pull the plugs and check the condition. If the scan tool has that capability, and the scan tool can operate the IMRC valves, then the problem is either resolved and a simple code clearing is all that's left or a new PCM would be called for. Find out what kind of system you have and verify that voltage to the fuel level sensor is present at the fuel pump wiring harness.
Diagnostic trouble code P2251 Seat 127 is not difficult to diagnose and repair. Thus, it always pays to have a qualified technician to look after your vehicle should this error code arise.
Diagnosing this code requires the engine to be in good running shape, without unmetered air entering the engine. If other codes that relates to misfiring condition, lean running or air entering the engine is present, then you must first fix those error codes before P2251 Seat 127.
Fortunately, P2251 Seat 127 is a fairly common OBD code, meaning that it applies to all makes and models of vehicles made after 1996.